Development of an action plan for acute food protein–induced enterocolitis syndrome in Japan

Yuri E. Kram, MD; Miori Sato, MD; Kiwako Yamamoto-Hanada, MD, PhD; Kenji Toyokuni, MD; Satoko Uematsu, MD, PhD; Takahiro Kudo, MD, PhD; Yoshiyuki Yamada, MD, PhD; Yoshikazu Ohtsuka, MD, PhD; Kenji Matsumoto, MD, PhD; Katsuhiro Arai, MD, PhD; Tatsuki Fukuie, MD, PhD; Ichiro Nomura, MD, PhD; Yukihiro Ohya, MD, PhD

World Allergy Organization Journal (May 2023)

Development of an action plan for acute food protein–induced enterocolitis syndrome in Japan

Yuri E. Kram, MD,
Miori Sato, MD,
Kiwako Yamamoto-Hanada, MD, PhD,
Kenji Toyokuni, MD,
Satoko Uematsu, MD, PhD,
Takahiro Kudo, MD, PhD,
Yoshiyuki Yamada, MD, PhD,
Yoshikazu Ohtsuka, MD, PhD,
Kenji Matsumoto, MD, PhD,
Katsuhiro Arai, MD, PhD,
Tatsuki Fukuie, MD, PhD,
Ichiro Nomura, MD, PhD,
Yukihiro Ohya, MD, PhD

Affiliations

Yuri E. Kram, MD: Allergy Center, National Center for Child Health and Development, Tokyo, Japan.
Miori Sato, MD: Allergy Center, National Center for Child Health and Development, Tokyo, Japan.
Kiwako Yamamoto-Hanada, MD, PhD: Allergy Center, National Center for Child Health and Development, Tokyo, Japan.; Corresponding author. Mailing address: 2-10-1, Okura, Setagayaku, Tokyo, 157-8535, Japan.
Kenji Toyokuni, MD: Allergy Center, National Center for Child Health and Development, Tokyo, Japan.
Satoko Uematsu, MD, PhD: Division of Emergency and Transport Services, National Center for Child Health and Development, Tokyo, Japan.
Takahiro Kudo, MD, PhD: Department of Pediatrics, Juntendo University Faculty of Medicine, Tokyo, Japan.
Yoshiyuki Yamada, MD, PhD: Department of Pediatrics, Tokai University School of Medicine, Kanagawa, Japan.
Yoshikazu Ohtsuka, MD, PhD: Department of Pediatrics, Juntendo University Faculty of Medicine, Tokyo, Japan.
Kenji Matsumoto, MD, PhD: Department of Allergy and Clinical Immunology, National Research Institute for Child Health and Development, Tokyo, Japan
Katsuhiro Arai, MD, PhD: Allergy Center, National Center for Child Health and Development, Tokyo, Japan.; Division of Gastroenterology, National Center for Child Health and Development, Tokyo, Japan.
Tatsuki Fukuie, MD, PhD: Allergy Center, National Center for Child Health and Development, Tokyo, Japan.
Ichiro Nomura, MD, PhD: Allergy Center, National Center for Child Health and Development, Tokyo, Japan.; Corresponding author. Mailing address: 2-10-1, Okura, Setagayaku, Tokyo, 157-8535, Japan.
Yukihiro Ohya, MD, PhD: Allergy Center, National Center for Child Health and Development, Tokyo, Japan.

Journal volume & issue: Vol. 16, no. 5
p. 100772

Abstract

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Reports of food protein–induced enterocolitis syndrome (FPIES) in Japan have been increasing. However, the disease itself and the treatment options are poorly understood by both patients and medical professionals. The objective of this study is to develop an action plan for acute FPIES in Japan. We prepared a single–sheet action plan that describes the management of acute FPIES episodes for caregivers on one side and medical professionals on the reverse side. To evaluate the content of the action plan, we distributed a questionnaire to caregivers of patients with FPIES and to physicians who would encounter patients with FPIES. Changes to the FPIES action plan were made based on the feedback from the participants. The Delphi method was utilized to finalize the action plan. The participants of the initial survey found the action plan to be useful but the process for determining severity to be impractical. After discussion, the authors made appropriate improvements. By the Delphi method, consensus was reached on the revised FPIES action plan. In conclusion, this Japanese FPIES action plan was created by physicians from multiple subspecialties and caregivers of patients with FPIES. The action plan may improve the management of acute FPIES reactions in the Japanese community.

Published in World Allergy Organization Journal

ISSN: 1939-4551 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Immunologic diseases. Allergy
Website: https://www.sciencedirect.com/journal/world-allergy-organization-journal

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