Targeting hypoxia-induced CBS expression inhibits breast cancer stem cells through the induction of ferroptosis

• Guangyao Wei,
• Jia Liu,
• Jie Lan,
• Guangyu Ji,
• Huize Xia,
• Zhiqun Zhao,
• Zhaoxue Yu,
• Rong Sun,
• Chuanzhao Zhang,
• Haiquan Lu

Affiliations

Guangyao Wei

The Second Hospital and Advanced Medical Research Institute, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China; Key Laboratory for Experimental Teratology of the Ministry of Education, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China

Jia Liu

The Second Hospital and Advanced Medical Research Institute, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China; Key Laboratory for Experimental Teratology of the Ministry of Education, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China

Jie Lan

Department of Radiation Oncology, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China

Guangyu Ji

The Second Hospital and Advanced Medical Research Institute, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China; Key Laboratory for Experimental Teratology of the Ministry of Education, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China

Huize Xia

The Second Hospital and Advanced Medical Research Institute, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China; Key Laboratory for Experimental Teratology of the Ministry of Education, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China

Zhiqun Zhao

The Second Hospital and Advanced Medical Research Institute, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China; Key Laboratory for Experimental Teratology of the Ministry of Education, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China

Zhaoxue Yu

Shandong Zhongke Institute for Regenerative Medicine, Jinan, Shandong 250012, China

Rong Sun

The Second Hospital and Advanced Medical Research Institute, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China

Chuanzhao Zhang

Department of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510080, China; Corresponding author. No. 106 Zhongshan 2nd Road, Guangzhou, Guangdong 510080, China.

Haiquan Lu

The Second Hospital and Advanced Medical Research Institute, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China; Key Laboratory for Experimental Teratology of the Ministry of Education, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China; Shandong Zhongke Institute for Regenerative Medicine, Jinan, Shandong 250012, China; Center for Reproductive Medicine, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China; Corresponding author. Room 211, Building 10, No.17922 Jingshi Road, Jinan, Shandong 250012, China.