Journal for ImmunoTherapy of Cancer (Nov 2020)

820 MCLA-145 is a bispecific IgG1 antibody that inhibits PD-1/PD-L1 signaling while simultaneously activating CD137 signaling on T cells

  • Jing Zhou,
  • Mark Throsby,
  • Lex Bakker,
  • Arpita Mondal,
  • Wilfred Marissen,
  • Paul Tacken,
  • Steef Engels,
  • Liang-Chuan Wang,
  • Patrick Mayes,
  • Cecile Geuijen,
  • Rinse Klooster,
  • Pieter Fokko Van Loo,
  • Yao-Bin Liu,
  • Arjen Kramer,
  • Thomas Condamine,
  • Alla Volgina,
  • Linda Hendriks,
  • Hans van der Maaden,
  • Eric Rovers,
  • Floris Fransen,
  • Renate den Blanken-Smit,
  • Vanessa Zondag-van der Zande,
  • Abdul Basmeleh,
  • Willem Bartelink,
  • Ashwini Kulkarni,
  • Cheng-Yen Huang,
  • Leslie Hall,
  • Shane Harvey,
  • Chrysi Kanellopoulou,
  • Shaun Stewart,
  • Horacio Nastri,
  • Ton Logtenberg,
  • Simon Plyte

DOI
https://doi.org/10.1136/jitc-2020-SITC2020.0820
Journal volume & issue
Vol. 8, no. Suppl 3

Abstract

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