Nature Communications (Mar 2023)

The crystal structure of a simian Foamy Virus receptor binding domain provides clues about entry into host cells

  • Ignacio Fernández,
  • Lasse Toftdal Dynesen,
  • Youna Coquin,
  • Riccardo Pederzoli,
  • Delphine Brun,
  • Ahmed Haouz,
  • Antoine Gessain,
  • Félix A. Rey,
  • Florence Buseyne,
  • Marija Backovic

DOI
https://doi.org/10.1038/s41467-023-36923-0
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 14

Abstract

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Foamy viruses are ancient retroviruses that are prevalent in non-human primates. Fernández et al. report an X-ray structure of a protein domain from a simian Foamy virus that mediates the attachment to cells, providing insights into viral entry.