Efficient conversion of carbohydrates into 5‐hydroxymethylfurfural using choline chloride-based deep eutectic solvents
Dung Kim Thi Ngo,
Trinh Hao Nguyen,
Phat Ngoc Nguyen,
Hai Truong Nguyen,
Trinh Ngoc Thi Huynh,
Ha Bich Phan,
Phuong Hoang Tran
Affiliations
Dung Kim Thi Ngo
Faculty of General Sciences, Tra Vinh University, Tra Vinh City, Tra Vinh Province, Viet Nam
Trinh Hao Nguyen
Department of Organic Chemistry, Faculty of Chemistry, University of Science, Ho Chi Minh City, Viet Nam; Vietnam National University, Ho Chi Minh City, Viet Nam
Phat Ngoc Nguyen
Department of Organic Chemistry, Faculty of Chemistry, University of Science, Ho Chi Minh City, Viet Nam; Vietnam National University, Ho Chi Minh City, Viet Nam
Hai Truong Nguyen
Department of Organic Chemistry, Faculty of Chemistry, University of Science, Ho Chi Minh City, Viet Nam; Vietnam National University, Ho Chi Minh City, Viet Nam
Trinh Ngoc Thi Huynh
Faculty of General Sciences, Tra Vinh University, Tra Vinh City, Tra Vinh Province, Viet Nam
Ha Bich Phan
Department of Organic Chemistry, Faculty of Chemistry, University of Science, Ho Chi Minh City, Viet Nam; Vietnam National University, Ho Chi Minh City, Viet Nam; Institute of Public Health, Ho Chi Minh City, Viet Nam
Phuong Hoang Tran
Department of Organic Chemistry, Faculty of Chemistry, University of Science, Ho Chi Minh City, Viet Nam; Vietnam National University, Ho Chi Minh City, Viet Nam; Corresponding author. Department of Organic Chemistry, Faculty of Chemistry, University of Science, Ho Chi Minh City, Viet Nam.
In this study, the conversion of monosaccharides to 5-hydroxymethylfurfural (5-HMF) using different deep eutectic solvents (DESs) was investigated in various conditions. Among all the investigated DESs, [ChCl][trichloroacetic acid], based on choline chloride and trichloroacetic acid with the ratio 1:1, showed the highest catalytic activity. A maximum 5-HMF yield was 82 % for 1 h at 100 °C using [ChCl][trichloroacetic acid] as a catalyst from fructose. [ChCl][trichloroacetic acid] could be recovered and reused three times with a slight loss in activity. Our work demonstrated the low-cost and effective method for the synthesis of 5-HMF from carbohydrates.
