USE OF ELECTROSPRAY MASS SPECTROMTERY TO STUDY THE INTERACTIONS BETWEEN PARA-SULPHONATO-CALIX[4]ARENE AND A SERIES OF SERUM ALBUMIN PROTEINS

Abstract

The binding of para-Sulphonato-calix[4]arene to a series of Serum Albumin Proteins has been studied using Electrospray Mass Spectrometry, each protein shows different capacities to interact with para-Sulphonato-calix[4]arene, including the number of ligands bound, the Association Constants observed, and the stoichiometries at which the onset of each binding event is observed.

Keywords

• Calix[n]arene
• para-Sulphonato-calix[4]arene
• Electrospray Mass Spectrometry
• Binding Constants
• Complex Stoichiometry
• Sequential Binding