Intravenous immunoglobulin as adjuvant therapy for COVID-19: A case report and literature review

Carlos A Flores-Oria; Emilio Saturno; Supriya Ramanathan; Diana J Martinez Castillo; Roshni Kumar; Nelson Ferrer; Afnan Mossaad; Maria E Tellez; Cindy Jon; Sara C Waters; Ricardo A Mosquera

doi:10.1177/2050313X211029699

SAGE Open Medical Case Reports (Jun 2021)

Intravenous immunoglobulin as adjuvant therapy for COVID-19: A case report and literature review

Carlos A Flores-Oria,
Emilio Saturno,
Supriya Ramanathan,
Diana J Martinez Castillo,
Roshni Kumar,
Nelson Ferrer,
Afnan Mossaad,
Maria E Tellez,
Cindy Jon,
Sara C Waters,
Ricardo A Mosquera

Affiliations

Carlos A Flores-Oria: Division of Pulmonology, Department of Pediatrics, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA
Emilio Saturno: West Jefferson Medical Center, Marrero, LA, USA
Supriya Ramanathan: Department of Pediatrics, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA
Diana J Martinez Castillo: Department of Pediatrics, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA
Roshni Kumar: Bellaire High School, Bellaire, TX, USA
Nelson Ferrer: Hospital Pacifica Salud, Panama
Afnan Mossaad: Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA
Maria E Tellez: School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA
Cindy Jon: Division of Pulmonology, Department of Pediatrics, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA
Sara C Waters: Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA
Ricardo A Mosquera: Division of Pulmonology, Department of Pediatrics, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA

DOI: https://doi.org/10.1177/2050313X211029699
Journal volume & issue: Vol. 9

Abstract

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Severe acute respiratory syndrome coronavirus 2 has infected and caused the death of an alarming number of individuals worldwide. No specific treatment has been internationally standardized for coronavirus disease 2019 (COVID-19); however, in some cases, intravenous immunoglobulin (IVIG) has been used as adjuvant treatment in critically ill patients with COVID-19 pneumonia. We report a case of a 50-year-old man with severe COVID-19 pneumonia who received 5 days course of IVIG as adjuvant therapy. Invasive respiratory support was avoided. The patient had a successful recovery and was discharged without supplemental oxygen. A high dose of IVIG may improve survival in patients with severe COVID-19 pneumonia. In the current report, we reviewed literature on how IVIG use may improve the early stages of the disease.

Published in SAGE Open Medical Case Reports

ISSN: 2050-313X (Online)
Publisher: SAGE Publishing
Country of publisher: United States
LCC subjects: Medicine: Medicine (General)
Website: https://journals.sagepub.com/home/sco

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