Comparison of beam segment versus full plan re-optimization in daily magnetic resonance imaging-guided online-adaptive radiotherapy

Janita E. van Timmeren; Madalyne Chamberlain; Jérôme Krayenbuehl; Lotte Wilke; Stefanie Ehrbar; Marta Bogowicz; Mariangela Zamburlini; Helena Garcia Schüler; Matea Pavic; Panagiotis Balermpas; Chaehee Ryu; Matthias Guckenberger; Nicolaus Andratschke; Stephanie Tanadini-Lang

Physics and Imaging in Radiation Oncology (Jan 2021)

Comparison of beam segment versus full plan re-optimization in daily magnetic resonance imaging-guided online-adaptive radiotherapy

Janita E. van Timmeren,
Madalyne Chamberlain,
Jérôme Krayenbuehl,
Lotte Wilke,
Stefanie Ehrbar,
Marta Bogowicz,
Mariangela Zamburlini,
Helena Garcia Schüler,
Matea Pavic,
Panagiotis Balermpas,
Chaehee Ryu,
Matthias Guckenberger,
Nicolaus Andratschke,
Stephanie Tanadini-Lang

Affiliations

Janita E. van Timmeren: Corresponding author at: Department of Radiation Oncology, University Hospital Zürich and University of Zürich, Rämistrasse 100, 8091 Zürich, Switzerland.; Department of Radiation Oncology, University Hospital Zürich and University of Zürich, Zürich, Switzerland
Madalyne Chamberlain: Department of Radiation Oncology, University Hospital Zürich and University of Zürich, Zürich, Switzerland
Jérôme Krayenbuehl: Department of Radiation Oncology, University Hospital Zürich and University of Zürich, Zürich, Switzerland
Lotte Wilke: Department of Radiation Oncology, University Hospital Zürich and University of Zürich, Zürich, Switzerland
Stefanie Ehrbar: Department of Radiation Oncology, University Hospital Zürich and University of Zürich, Zürich, Switzerland
Marta Bogowicz: Department of Radiation Oncology, University Hospital Zürich and University of Zürich, Zürich, Switzerland
Mariangela Zamburlini: Department of Radiation Oncology, University Hospital Zürich and University of Zürich, Zürich, Switzerland
Helena Garcia Schüler: Department of Radiation Oncology, University Hospital Zürich and University of Zürich, Zürich, Switzerland
Matea Pavic: Department of Radiation Oncology, University Hospital Zürich and University of Zürich, Zürich, Switzerland
Panagiotis Balermpas: Department of Radiation Oncology, University Hospital Zürich and University of Zürich, Zürich, Switzerland
Chaehee Ryu: Department of Radiation Oncology, University Hospital Zürich and University of Zürich, Zürich, Switzerland
Matthias Guckenberger: Department of Radiation Oncology, University Hospital Zürich and University of Zürich, Zürich, Switzerland
Nicolaus Andratschke: Department of Radiation Oncology, University Hospital Zürich and University of Zürich, Zürich, Switzerland
Stephanie Tanadini-Lang: Department of Radiation Oncology, University Hospital Zürich and University of Zürich, Zürich, Switzerland

Journal volume & issue: Vol. 17
pp. 43 – 46

Abstract

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The optimal approach for magnetic resonance imaging-guided online adaptive radiotherapy is currently unknown and needs to consider patient on-couch time constraints. The aim of this study was to compare two different plan optimization approaches. The comparison was performed in 238 clinically applied online-adapted treatment plans from 55 patients, in which the approach of re-optimization was selected based on the physician’s choice. For 33 patients where both optimization approaches were used at least once, the median treatment planning dose metrics of both target and organ at risk differed less than 1%. Therefore, we concluded that beam segment weight optimization was chosen adequately for most patients without compromising plan quality.

Published in Physics and Imaging in Radiation Oncology

ISSN: 2405-6316 (Online)
Publisher: Elsevier
Country of publisher: Ireland
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine; Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Website: https://www.journals.elsevier.com/physics-and-imaging-in-radiation-oncology/

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