S119: CEBPA AND TET2 MUTATIONS COOPERATE TO INDUCE AGGRESSIVE AML VIA GATA-2 DOWNREGULATION

• E. Heyes,
• A. S. Wilhelmson,
• A. Wenzel,
• M. B. Schuster,
• M. Ali,
• T. D’Altri,
• T. Eder,
• G. Manhart,
• E. Rzepa,
• L. Schmidt,
• M. Meggendorfer,
• T. Haferlach,
• G. Volpe,
• C. Nerlov,
• J. Frampton,
• K. Jae Won,
• F. Grebien,
• B. Porse

Affiliations

E. Heyes

1 Institute of Medical Biochemistry, University of Veterinary Medicine Vienna, Vienna, Austria

A. S. Wilhelmson

2 The Finsen Laboratory, Rigshospitalet, Faculty of Health Sciences

A. Wenzel

2 The Finsen Laboratory, Rigshospitalet, Faculty of Health Sciences

M. B. Schuster

2 The Finsen Laboratory, Rigshospitalet, Faculty of Health Sciences

M. Ali

3 Biotech Research and Innovation Center (BRIC)

T. D’Altri

2 The Finsen Laboratory, Rigshospitalet, Faculty of Health Sciences

T. Eder

1 Institute of Medical Biochemistry, University of Veterinary Medicine Vienna, Vienna, Austria

G. Manhart

1 Institute of Medical Biochemistry, University of Veterinary Medicine Vienna, Vienna, Austria

E. Rzepa

1 Institute of Medical Biochemistry, University of Veterinary Medicine Vienna, Vienna, Austria

L. Schmidt

1 Institute of Medical Biochemistry, University of Veterinary Medicine Vienna, Vienna, Austria

M. Meggendorfer

5 MLL Munich Leukemia Laboratory, München, Germany

T. Haferlach

5 MLL Munich Leukemia Laboratory, München, Germany

G. Volpe

6 Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham

C. Nerlov

7 MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom

J. Frampton

6 Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham

K. Jae Won

3 Biotech Research and Innovation Center (BRIC)

F. Grebien

1 Institute of Medical Biochemistry, University of Veterinary Medicine Vienna, Vienna, Austria

B. Porse

2 The Finsen Laboratory, Rigshospitalet, Faculty of Health Sciences