Research into Morphofunctional Characteristics of Erythrocytes in COVID-19 Patients

Victor Revin; Larisa Balykova; Sergey Pinyaev; Ilya Syusin; Olga Radaeva; Nadezhda Revina; Yuliya Kostina; Evgeniy Kozlov; Vera Inchina; Igor Nikitin; Alexandr Salikov; Ilya Fedorov

doi:10.3390/biomedicines10030553

Biomedicines (Feb 2022)

Research into Morphofunctional Characteristics of Erythrocytes in COVID-19 Patients

Victor Revin,
Larisa Balykova,
Sergey Pinyaev,
Ilya Syusin,
Olga Radaeva,
Nadezhda Revina,
Yuliya Kostina,
Evgeniy Kozlov,
Vera Inchina,
Igor Nikitin,
Alexandr Salikov,
Ilya Fedorov

Affiliations

Victor Revin: Federal State Budgetary Educational Institution of Higher Education, Ogarev Mordovia State University, 430005 Saransk, Russia
Larisa Balykova: Federal State Budgetary Educational Institution of Higher Education, Ogarev Mordovia State University, 430005 Saransk, Russia
Sergey Pinyaev: Federal State Budgetary Educational Institution of Higher Education, Ogarev Mordovia State University, 430005 Saransk, Russia
Ilya Syusin: Federal State Budgetary Educational Institution of Higher Education, Ogarev Mordovia State University, 430005 Saransk, Russia
Olga Radaeva: Federal State Budgetary Educational Institution of Higher Education, Ogarev Mordovia State University, 430005 Saransk, Russia
Nadezhda Revina: Federal State Budgetary Educational Institution of Higher Education, Ogarev Mordovia State University, 430005 Saransk, Russia
Yuliya Kostina: Federal State Budgetary Educational Institution of Higher Education, Ogarev Mordovia State University, 430005 Saransk, Russia
Evgeniy Kozlov: Federal State Budgetary Educational Institution of Higher Education, Ogarev Mordovia State University, 430005 Saransk, Russia
Vera Inchina: Federal State Budgetary Educational Institution of Higher Education, Ogarev Mordovia State University, 430005 Saransk, Russia
Igor Nikitin: Federal State Autonomous Institution, Treatment and Rehabilitation Center of the Ministry of Health of the Russian Federation, 125367 Moscow, Russia
Alexandr Salikov: State Budgetary Institution of Healthcare, City Clinical Hospital after V.M. Buyanov of the Moscow Department of Health, 115516 Moscow, Russia
Ilya Fedorov: State Budgetary Institution of Healthcare, City Clinical Hospital after V.M. Buyanov of the Moscow Department of Health, 115516 Moscow, Russia

DOI: https://doi.org/10.3390/biomedicines10030553
Journal volume & issue: Vol. 10, no. 3
p. 553

Abstract

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In this paper, the erythrocytes of healthy donors and people with a confirmed diagnosis of COVID-19 were tested by Raman spectroscopy and laser interference microscopy. We argue that erythrocytes (red blood cells) in COVID-19 patients have an irregular shape, and their morphometric characteristics are impaired in comparison to healthy red blood cells. Raman spectroscopy also allows us to detect a decreased oxygen transport function of these erythrocytes. The combination of these methods—Raman spectroscopy and laser interference microscopy—is a highly effective method for the diagnosis of SARS-CoV-2.

Published in Biomedicines

ISSN: 2227-9059 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Biology (General)
Website: http://www.mdpi.com/journal/biomedicines

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Abstract

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