THE ROLE OF HYPOXIA-INDUCED FACTOR-1 (HIF-1) IN CYTOPROTECTION EFFECT IN ISCHEMIC AND PHARMACOLOGIC POSTCONDITIONING

Abstract

The review concerns on the experimental studies results of the influence of ischemic and pharmacological post conditioning of the liver, brain, myocardium and scelet muscle on the expression and activity of the hypoxia-induced factor-1α (HIF-1α) in various types of lab animals.

Keywords

• postconditioning
• hypoxia-induced factor (hif)
• ischemia-reperfusion
• heart
• liver
• brain