Calcified Sister Mary Joseph nodule as the presenting complaint of advanced low-grade serous ovarian cancer

Abstract

A healthy 38-year-old woman presented with a hard umbilical mass that has been growing for a few months in duration with no other significant symptoms and signs. Computed tomography images identified a lobulated densely calcified umbilical mass, left ovarian cysts, a subcentimeter calcified omental nodule, and nonspecific punctate pelvic calcifications. Histopathology of the mass revealed low-grade serous carcinoma with postsurgical diagnosis of International Federation of Gynecology and Obstetrics (FIGO) stage IV ovarian cancer. This case presentation emphasizes the importance of increased awareness of interpreting radiologists of a seemingly benign appearing imaging finding such as umbilical calcification on CT as a sign of intra-abdominal/pelvic malignancies.

Keywords

• Sister Mary Joseph nodule
• Umbilical mass
• Serous ovarian cancer
• Umbilical lymphadenopathy
• Calcified umbilical mass
• Metastatic cancer