Co-morbidities in Patients Presenting with Gout at Tertiary Care Hospital Peshawar, A Cross Sectional Study, 2021 Pakistan

Abstract

Background: Gout is one of the most prevalent inflammatory arthritis in the world. It is associated with non-modifiable factors like age gender and genetics and modifiable risk factors like life style changes. Objective: To determine the co-morbidities of gout in patients presenting at tertiary care hospital Peshawar. Study type, settings & duration: A descriptive cross sectional study was conducted at Department of Rheumatology, Lady Reading Hospital, Peshawar from January 2021 to August 2021. Methodology: In this study a total of 323 patients fulfilling the inclusion and exclusion criteria of Gout were observed. All the patients in age between 16-80 years, either gender presenting with gout were included in the study. Gout was diagnosed as per American College of Rheumatology (ACR) Gout Classification Criteria.All the information i.e. age, gender and comorbidities were recorded and were analyzed in statistical software SPSS version 23. Results: A total of 323 patients were enrolled in the study, mean age was 42 with SD ±12.49,female predominance was noted with percentage of 71.8%.The most common comorbidities associated with gout were hypertension(61.6%) and obesity (68.1%). We had patients with other co-existing inflammatory and non-inflammatory Rheumatological diseases. These included seropositive and seronegative Rheumatoid arthritis, Polymyalgia Rheumatica PMR, connective tissue disorder CTD and psoriasis were rarely reported. Among non-inflammatory RMDs, vitamin D deficiency was found to be highly prevalent, followed by Osteoarthritis, Spondylitis and Radiculopathies. Conclusion: Our study concludes that the most common co-morbidities of gout were hypertension and obesity followed by other Rheumatologic diseases (RMDs) and vitamin D deficiency.

Keywords

• gout
• gender