EFFECT OF MONENSIN, AN IONOPHORE ANTIBIOTIC ON SERUM BIOCHEMICAL PROFILE IN BROILER CHICKEN

Abstract

Monensin, an ionophore antibiotic fed to broiler chicken at the rate of 121 (recommended use level), 363 and 726 ppm produced a significant and dose dependent increase in the activity of serum aspartate transaminase (AST), alanine transaminase (ALT), lactate dehydrogenase (LDH) and creatine phosphokinase (CPK) indicating hepatic, cardiac and skeletal muscle damaging potentials of the compound.