Терапевтический архив (Jun 2008)

Prevalence of subnormal glomerular filtration rate in patients with diabetes mellitus

  • I I Trofimenko,
  • V A Dobronravov,
  • N N Bystrova,
  • Iu V Drozdova,
  • O V Galkina,
  • A V Smirnov

Journal volume & issue
Vol. 80, no. 6
pp. 48 – 52

Abstract

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Aim. To evaluate prevalence of subnormal glomerular filtration rate (GFR) in diabetes mellitus (DM) patients with reference to albuminuria level. Material and methods. GFR by MDRD and urine excretion of protein/albumin were estimated in 851 diabetic patients (473 with type 1 DM and 378 with type 2 DM). Results. Normoalbuminuria (NAU), microalbuminuria (MAU) and proteinuria were detected in 54, 16 and 30% type 1 diabetics, respectively; 77% had subnormal GFR, in NAU 8.3% had GFR decline (

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