Nature Communications (Jan 2019)

Completion of the cytosolic post-chorismate phenylalanine biosynthetic pathway in plants

  • Yichun Qian,
  • Joseph H. Lynch,
  • Longyun Guo,
  • David Rhodes,
  • John A. Morgan,
  • Natalia Dudareva

DOI
https://doi.org/10.1038/s41467-018-07969-2
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 15

Abstract

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Phenylalanine is mostly synthesized in plant plastids, but cytosolic transamination of phenylpyruvate also contributes. Here the authors show that a cytosolic chorismate mutase and a prephenate dehydratase encoded by an isoform of the plastidial ADT3 enzyme, produce phenylpyruvate in the cytosol.