Enabling comprehensive optogenetic studies of mouse hearts by simultaneous opto-electrical panoramic mapping and stimulation

Michael Rieger; Christian Dellenbach; Johannes vom Berg; Jane Beil-Wagner; Ange Maguy; Stephan Rohr

doi:10.1038/s41467-021-26039-8

Nature Communications (Oct 2021)

Enabling comprehensive optogenetic studies of mouse hearts by simultaneous opto-electrical panoramic mapping and stimulation

Michael Rieger,
Christian Dellenbach,
Johannes vom Berg,
Jane Beil-Wagner,
Ange Maguy,
Stephan Rohr

Affiliations

Michael Rieger: Department of Physiology, University of Bern
Christian Dellenbach: Department of Physiology, University of Bern
Johannes vom Berg: Institute of Laboratory Animal Science, University of Zürich
Jane Beil-Wagner: Institute of Laboratory Animal Science, University of Zürich
Ange Maguy: Department of Physiology, University of Bern
Stephan Rohr: Department of Physiology, University of Bern

DOI: https://doi.org/10.1038/s41467-021-26039-8
Journal volume & issue: Vol. 12, no. 1
pp. 1 – 13

Abstract

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Current cardiac mapping systems provide either electrical or optical readouts. Here the authors report a panoramic opto-electrical measurement and stimulation (POEMS) system which embraces the entire ventricular surface of mouse hearts, allowing flexible combinations of optical and electrical recording and stimulation modalities.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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