Vitamin B Deficiency Does not Affect the Liver Concentrations of the Other Seven Kinds of B-Group Vitamins in Rats

Abstract

We aimed to determine the effects of vitamin B 1 deficiency on vitamin contents of urine, liver, and blood. In the current study, rats were divided into 3 groups (n = 5, each group): the first was freely fed a complete diet (ad lib-fed control group); the second freely fed a vitamin B 1 -free diet (vitamin B 1 deficient group); and the third pair-fed a complete diet with the same amounts of the vitamin B 1 deficient group (pair-fed control group). The experimental period was for 15 days. The blood concentrations of vitamin B 2 , PLP, vitamin B 12 , folic acid, and biotin were lower in the pair-fed control than in the ad lib-fed control and those of nicotinamide and pantothenic acid were the same. We conclude that Vitamin B 1 deficiency did not affect concentrations of the other B-group vitamins.