Poor sleep quality is negatively associated with low cognitive performance in general population independent of self-reported sleep disordered breathing

Zhongrong Wang; Mulalibieke Heizhati; Lin Wang; Mei Li; Zhikang Yang; Mengyue Lin; Reyila Abudereyimu; Jing Hong; Wenbo Yang; Ling Yao; Shasha Liu; Junli Hu; Nanfang Li

doi:10.1186/s12889-021-12417-w

BMC Public Health (Jan 2022)

Poor sleep quality is negatively associated with low cognitive performance in general population independent of self-reported sleep disordered breathing

Zhongrong Wang,
Mulalibieke Heizhati,
Lin Wang,
Mei Li,
Zhikang Yang,
Mengyue Lin,
Reyila Abudereyimu,
Jing Hong,
Wenbo Yang,
Ling Yao,
Shasha Liu,
Junli Hu,
Nanfang Li

Affiliations

Zhongrong Wang: Hypertension Center of People’s Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Hypertension Institute National Health Committee Key Laboratory of Hypertension Clinical Research
Mulalibieke Heizhati: Hypertension Center of People’s Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Hypertension Institute National Health Committee Key Laboratory of Hypertension Clinical Research
Lin Wang: Hypertension Center of People’s Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Hypertension Institute National Health Committee Key Laboratory of Hypertension Clinical Research
Mei Li: Hypertension Center of People’s Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Hypertension Institute National Health Committee Key Laboratory of Hypertension Clinical Research
Zhikang Yang: Hypertension Center of People’s Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Hypertension Institute National Health Committee Key Laboratory of Hypertension Clinical Research
Mengyue Lin: Hypertension Center of People’s Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Hypertension Institute National Health Committee Key Laboratory of Hypertension Clinical Research
Reyila Abudereyimu: Hypertension Center of People’s Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Hypertension Institute National Health Committee Key Laboratory of Hypertension Clinical Research
Jing Hong: Hypertension Center of People’s Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Hypertension Institute National Health Committee Key Laboratory of Hypertension Clinical Research
Wenbo Yang: Hypertension Center of People’s Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Hypertension Institute National Health Committee Key Laboratory of Hypertension Clinical Research
Ling Yao: Hypertension Center of People’s Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Hypertension Institute National Health Committee Key Laboratory of Hypertension Clinical Research
Shasha Liu: Hypertension Center of People’s Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Hypertension Institute National Health Committee Key Laboratory of Hypertension Clinical Research
Junli Hu: Hypertension Center of People’s Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Hypertension Institute National Health Committee Key Laboratory of Hypertension Clinical Research
Nanfang Li: Hypertension Center of People’s Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Hypertension Institute National Health Committee Key Laboratory of Hypertension Clinical Research

DOI: https://doi.org/10.1186/s12889-021-12417-w
Journal volume & issue: Vol. 22, no. 1
pp. 1 – 9

Abstract

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Abstract Background Sleep disordered breathing (SDB) plays a significant role in both sleep quality and cognition and whether it has an impact on the relationship between above two factors remains to be clear. The study aimed to explore the association between sleep quality and cognitive performance in general population by considering influence of sleep disordered breathing (SDB). Methods In this cross-sectional study, we enrolled subjects aged ≥ 18 years using a multi-stage random sampling method. Cognitive status was assessed using Mini Mental State Examination (MMSE) questionnaire, sleep quality using Pittsburgh Sleep Quality Index (PSQI) and SDB was assessed using No-SAS scale, respectively. Multi-variable logistic regression was applied to examine the association of sleep quality and cognitive performance. Subgroup analyses were performed in different age groups, and in those with and without SDB. Results Finally, 30,872 participants aged 47.5 ± 13.8 years with 53.5% women were enrolled, of whom 32.4% had poor sleep quality and 18.6% had low cognitive performance. Compared with good sleepers, subjects with poor sleep quality exhibited significantly higher presence of low cognitive performance (23.7% vs 16.2%, P < 0.001). Poor sleepers revealed 1.26 (95%CI: 1.16,1.36), 1.26 (1.08,1.46) and 1.25 (1.14,1.37) fold odds for low cognitive performance in general population and in subjects with and without self-reported SDB respectively. Stratified by age and SDB, the association was observed in young and middle-aged group without SDB (OR = 1.44, 95%CI: 1.30,1.59) and in the elderly group with SDB (OR = 1.30, 95%CI: 1.07,1.58). Conclusions Sleep quality is in a negative association with cognitive performance in general population independent of SDB, implying improvement of sleep disturbances is a potential objective of intervention strategies for cognitive protection at population level.

Published in BMC Public Health

ISSN: 1471-2458 (Online)
Publisher: BMC
Country of publisher: United Kingdom
LCC subjects: Medicine: Public aspects of medicine
Website: https://bmcpublichealth.biomedcentral.com

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