APL Materials (May 2019)

First proof-of-principle of inorganic perovskites clinical radiotherapy dosimeters

  • Mara Bruzzi,
  • Cinzia Talamonti,
  • Nicola Calisi,
  • Stefano Caporali,
  • Anna Vinattieri

DOI
https://doi.org/10.1063/1.5083810
Journal volume & issue
Vol. 7, no. 5
pp. 051101 – 051101-6

Abstract

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Inorganic CsPbBr3 perovskite devices have been manufactured and tested as dosimeters under both conventional and Intensity Modulated Radiotherapy (IMRT) X-ray beams. Samples showed a very good linear dependence of the collected charge/current on dose/dose rates in the range of 0.1–5.0 Gy/0.1–4.0 Gy/min of interest for clinical applications. A device sensitivity of about 70 nC/Gy mm3 compares favorably with other solid-state dosimeters. The first verification of an IMRT dose profile of a prostate cancer treatment, performed by moving the perovskite device on a 10 cm-long profile with a 0.5 mm pitch, showed agreement within 5% with the dose distribution required by the treatment planning system.