Mini-BLAST: computer systems to search for the pattern sequences in the bioinformatics databases

Abstract

Bioinformatics focuses on developing and applying computationally intensive techniques to increase the understanding of biological processes. In this report we de- scribe the compact computer system Mini-BLAST, designed to find DNA sequences in bioinformatics databases placed in local or web configurations. Our system allows the identification of gene sequences relating to new patterns (metagenome) that are not yet identified in such databases, containing data on known nucleotides. Such a task is a quite expensive and time consuming operation; therefore, for large genomes parallel algorithms are required. We developed a user-friendly graphical interface that allows the simple input of query data and outputs representative statistical analysis. Additionally, users can select particular databases for cases when a specific alignment is required. Although the package is developed in MS .NET 3.5/4.0 Visual C# system, it works with no limitations in Linux through the Mono framework.

Keywords

• bioinformática
• sistemas para la búsqueda de secuencias de ADN
• algoritmos paralelos
• GUI