Study of the role of erythrocyte and leukocyte intoxication indexes in the pathogenesis of experimental peritonitis

Abstract

The article presents the results of studying the role of erythrocyte and leukocyte indices of intoxication in the pathogenesis of experimental peritonitis. When studying the role of erythrocyte and leukocyte indices, a unidirectional trend of their change was revealed. An increase in the erythrocyte index of intoxication in the pathogenesis of experimental fecal peritonitis was established, most pronounced on the 10th day of the experiment (the level of EII increased by 107% compared to intact animals). The results of the study of the leukocyte intoxication index indicate a unidirectional trend, as in the case of the erythrocyte intoxication index. On the first day, the leukocyte index of intoxication increased on 225% (р<0.05), on the 4th day – on 256.7% (р<0.05), and on the 10th day – on 260% (р <0.05) compared to intact animals. It has been proven that the leukocyte index of intoxication is a more sensitive marker compared to the erythrocyte index.

Keywords

• peritonitis
• leukocyte index of intoxication
• erythrocyte index of intoxication
• pathogenesis