Is Protein BLAST a thing of the past?

Ali Al-Fatlawi; Martin Menzel; Michael Schroeder

doi:10.1038/s41467-023-44082-5

Nature Communications (Dec 2023)

Is Protein BLAST a thing of the past?

Ali Al-Fatlawi,
Martin Menzel,
Michael Schroeder

Affiliations

Ali Al-Fatlawi: Biotechnology Center (BIOTEC), Center for Molecular and Cellular Bioengineering, Technische Universität Dresden
Martin Menzel: Biotechnology Center (BIOTEC), Center for Molecular and Cellular Bioengineering, Technische Universität Dresden
Michael Schroeder: Biotechnology Center (BIOTEC), Center for Molecular and Cellular Bioengineering, Technische Universität Dresden

DOI: https://doi.org/10.1038/s41467-023-44082-5
Journal volume & issue: Vol. 14, no. 1
pp. 1 – 3

Abstract

Read online

Will protein structure search tools like AlphaFold replace protein sequence search with BLAST? We discuss the promises, using structure search for remote homology detection, and why protein BLAST, as the leading sequence search tool, should strive to incorporate structural information

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

About the journal