Isovitexin modulates autophagy in Alzheimer’s disease via miR-107 signalling

Cheng Jiang; Wang Guowei; Zhang Na; Li Fang; Shi Lina; Li Haining

doi:10.1515/tnsci-2020-0109

Translational Neuroscience (Oct 2020)

Isovitexin modulates autophagy in Alzheimer’s disease via miR-107 signalling

Cheng Jiang,
Wang Guowei,
Zhang Na,
Li Fang,
Shi Lina,
Li Haining

Affiliations

Cheng Jiang: Department of Neurology, General Hospital of Ningxia Medical University, Ningxia Key Laboratory of Cerebrocranial Diseases, Incubation Base of National Key Laboratory, Yinchuan, 750004, China
Wang Guowei: School of Clinical Medicine, Ningxia Medical University, Yinchuan, 750004, China
Zhang Na
Li Fang: Department of Neurology, General Hospital of Ningxia Medical University, Ningxia Key Laboratory of Cerebrocranial Diseases, Incubation Base of National Key Laboratory, Yinchuan, 750004, China
Shi Lina: Department of Neurology, General Hospital of Ningxia Medical University, Ningxia Key Laboratory of Cerebrocranial Diseases, Incubation Base of National Key Laboratory, Yinchuan, 750004, China
Li Haining: Department of Neurology, General Hospital of Ningxia Medical University, Ningxia Key Laboratory of Cerebrocranial Diseases, Incubation Base of National Key Laboratory, Yinchuan, 750004, China

DOI: https://doi.org/10.1515/tnsci-2020-0109
Journal volume & issue: Vol. 11, no. 1
pp. 391 – 401

Abstract

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Alzheimer’s disease (AD) is an ultimately fatal, degenerative brain disease in the elderly people. In the current work, we assessed the defensive capability of isovitexin (IVX) through an intracerebroventricular injection of streptozotocin (STZ)-induced AD mouse model.

Published in Translational Neuroscience

ISSN: 2081-6936 (Online)
Publisher: De Gruyter
Country of publisher: Poland
LCC subjects: Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry
Website: http://www.degruyter.com/view/j/tnsci

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