Nature Communications (Apr 2019)

Structure of the plastic-degrading Ideonella sakaiensis MHETase bound to a substrate

  • Gottfried J. Palm,
  • Lukas Reisky,
  • Dominique Böttcher,
  • Henrik Müller,
  • Emil A. P. Michels,
  • Miriam C. Walczak,
  • Leona Berndt,
  • Manfred S. Weiss,
  • Uwe T. Bornscheuer,
  • Gert Weber

DOI
https://doi.org/10.1038/s41467-019-09326-3
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 10

Abstract

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Plastic polymer PET degrading enzymes are of great interest for achieving sustainable plastics recycling. Here, the authors present the crystal structures of the plastic degrading bacterial enzymes PETase, MHETase in its apo-form and MHETase bound to a non-hydrolyzable substrate analog.