Lycoplanines B-D, Three Lycopodium Alkaloids from Lycopodium complanatum

Abstract

Abstract A novel C17N Lycopodium alkaloid (LA), lycoplanine B (1), containing an unusual formyl group, along with two new LAs, lycoplanines C (2) and D (3), were isolated from the whole plant of Lycopodium complanatum. Their structures were elucidated by extensive NMR techniques, including 1D- and 2D-NMR experiments, as well as comparing their spectral data with those of the known analogues. A possible biogenetic pathway for 1 was also proposed. Graphical Abstract

Keywords

• Lycopodium complanatum
• Lycoplanines
• Lycopodium alkaloids
• Anti-AChE activity