Journal of Clinical Medicine (Apr 2023)

Hypertensive Heart Disease—The Imaging Perspective

  • Tevfik F. Ismail,
  • Simon Frey,
  • Beat A. Kaufmann,
  • David J. Winkel,
  • Daniel T. Boll,
  • Michael J. Zellweger,
  • Philip Haaf

DOI
https://doi.org/10.3390/jcm12093122
Journal volume & issue
Vol. 12, no. 9
p. 3122

Abstract

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Hypertensive heart disease (HHD) develops in response to the chronic exposure of the left ventricle and left atrium to elevated systemic blood pressure. Left ventricular structural changes include hypertrophy and interstitial fibrosis that in turn lead to functional changes including diastolic dysfunction and impaired left atrial and LV mechanical function. Ultimately, these changes can lead to heart failure with a preserved (HFpEF) or reduced (HFrEF) ejection fraction. This review will outline the clinical evaluation of a patient with hypertension and/or suspected HHD, with a particular emphasis on the role and recent advances of multimodality imaging in both diagnosis and differential diagnosis.

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