Journal of the Serbian Chemical Society (Jan 2015)

Facile synthesis of water-soluble curcumin nanocrystals

  • Marković Zoran M.,
  • Prekodravac Jovana R.,
  • Tošić Dragana D.,
  • Holclajtner-Antunović Ivanka D.,
  • Milosavljević Momir S.,
  • Dramićanin Miroslav D.,
  • Todorović-Marković Biljana M.

DOI
https://doi.org/10.2298/JSC140819117M
Journal volume & issue
Vol. 80, no. 1
pp. 63 – 72

Abstract

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In this paper, facile synthesis of water soluble curcumin nanocrystals is reported. Solvent exchange method was applied to synthesize curcumin nanocrystals. Different techniques were used to characterize the structural and photophysical properties of curcumin nanocrystals. We found that nanocurcumin prepared by this method had good chemical and physical stability, could be stored in the powder form at room temperature, and was freely dispersible in water. It was established that the size of curcumin nanocrystals was varied in the range of 20-500 nm. Fourier transform infrared spectroscopy and UV-Vis analyses showed the presence of tetrahydrofuran inside the curcumin nanocrystals. Also, it was found that nanocurcumin emitted photoluminescencewith yellow-green colour. [Projekat Ministarstva nauke Republike Srbije, br. 172003]

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