Magnetic resonance imaging analysis predicts nanoparticle concentration delivered to the brain parenchyma

Affiliations

Michael Plaksin: Insightec Company Ltd
Tiran Bercovici: Insightec Company Ltd
Gabriella Gabi Sat Toltsis: Insightec Company Ltd
Javier Grinfeld: Insightec Company Ltd
Boaz Shapira: Insightec Company Ltd
Yuval Zur: Insightec Company Ltd
Rafi de Picciotto: Insightec Company Ltd
Eyal Zadicario: Insightec Company Ltd
Mustaffa Siddeeq: Neuro Oncology Unit, Sheba Medical Center, Ramat Gan, Affiliated with the Sackler School of Medicine Tel Aviv University
Anton Wohl: Neuro Oncology Unit, Sheba Medical Center, Ramat Gan, Affiliated with the Sackler School of Medicine Tel Aviv University
Zion Zibly: Neuro Oncology Unit, Sheba Medical Center, Ramat Gan, Affiliated with the Sackler School of Medicine Tel Aviv University
Yoav Levy: Insightec Company Ltd
Zvi R. Cohen: Neuro Oncology Unit, Sheba Medical Center, Ramat Gan, Affiliated with the Sackler School of Medicine Tel Aviv University

Abstract

ΔR2* values from MRI analysis correlate with concentrations of liposomes in the size range of 18–44 nm in a rat model.