Vaccines against Emerging and Neglected Infectious Diseases: An Overview

Larissa Vuitika; Wasim A. Prates-Syed; Jaqueline Dinis Queiros Silva; Karin P. Crema; Nelson Côrtes; Aline Lira; Julia Beatriz Menuci Lima; Niels Olsen Saraiva Camara; Lena F. Schimke; Otavio Cabral-Marques; Mohammad Sadraeian; Lorena C. S. Chaves; Gustavo Cabral-Miranda

doi:10.3390/vaccines10091385

Vaccines (Aug 2022)

Vaccines against Emerging and Neglected Infectious Diseases: An Overview

Larissa Vuitika,
Wasim A. Prates-Syed,
Jaqueline Dinis Queiros Silva,
Karin P. Crema,
Nelson Côrtes,
Aline Lira,
Julia Beatriz Menuci Lima,
Niels Olsen Saraiva Camara,
Lena F. Schimke,
Otavio Cabral-Marques,
Mohammad Sadraeian,
Lorena C. S. Chaves,
Gustavo Cabral-Miranda

Affiliations

Larissa Vuitika: Department of Immunology, Institute of Biomedical Sciences IV, University of São Paulo (ICB-IV/USP), São Paulo 05508-000, SP, Brazil
Wasim A. Prates-Syed: Department of Immunology, Institute of Biomedical Sciences IV, University of São Paulo (ICB-IV/USP), São Paulo 05508-000, SP, Brazil
Jaqueline Dinis Queiros Silva: Laboratory of Research in Infectious Diseases (LAPI), Hospital Prof. Edgard Santos, Federal University of Bahia, Salvador 40110-060, BA, Brazil
Karin P. Crema: Department of Immunology, Institute of Biomedical Sciences IV, University of São Paulo (ICB-IV/USP), São Paulo 05508-000, SP, Brazil
Nelson Côrtes: Department of Immunology, Institute of Biomedical Sciences IV, University of São Paulo (ICB-IV/USP), São Paulo 05508-000, SP, Brazil
Aline Lira: Department of Immunology, Institute of Biomedical Sciences IV, University of São Paulo (ICB-IV/USP), São Paulo 05508-000, SP, Brazil
Julia Beatriz Menuci Lima: Department of Immunology, Institute of Biomedical Sciences IV, University of São Paulo (ICB-IV/USP), São Paulo 05508-000, SP, Brazil
Niels Olsen Saraiva Camara: Department of Immunology, Institute of Biomedical Sciences IV, University of São Paulo (ICB-IV/USP), São Paulo 05508-000, SP, Brazil
Lena F. Schimke: Department of Immunology, Institute of Biomedical Sciences IV, University of São Paulo (ICB-IV/USP), São Paulo 05508-000, SP, Brazil
Otavio Cabral-Marques: Department of Immunology, Institute of Biomedical Sciences IV, University of São Paulo (ICB-IV/USP), São Paulo 05508-000, SP, Brazil
Mohammad Sadraeian: Institute for Biomedical Materials and Devices (IBMD), Faculty of Science, University of Technology, Sydney, NSW 2007, Australia
Lorena C. S. Chaves: Department of Microbiology and Immunology, School of Medicine, Emory University, Claudia Nance Rollins Building, Atlanta, GA 30329, USA
Gustavo Cabral-Miranda: Department of Immunology, Institute of Biomedical Sciences IV, University of São Paulo (ICB-IV/USP), São Paulo 05508-000, SP, Brazil

DOI: https://doi.org/10.3390/vaccines10091385
Journal volume & issue: Vol. 10, no. 9
p. 1385

Abstract

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Neglected Tropical Diseases (NTDs) are a group of diseases that are highly prevalent in tropical and subtropical regions, and closely associated with poverty and marginalized populations. Infectious diseases affect over 1.6 billion people annually, and vaccines are the best prophylactic tool against them. Along with NTDs, emerging and reemerging infectious diseases also threaten global public health, as they can unpredictably result in pandemics. The recent advances in vaccinology allowed the development and licensing of new vaccine platforms that can target and prevent these diseases. In this work, we discuss the advances in vaccinology and some of the difficulties found in the vaccine development pipeline for selected NTDs and emerging and reemerging infectious diseases, including HIV, Dengue, Ebola, Chagas disease, malaria, leishmaniasis, zika, and chikungunya.

Published in Vaccines

ISSN: 2076-393X (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Medicine
Website: http://www.mdpi.com/journal/vaccines

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