Recent advances in the biomolecules mediated synthesis of nanoclusters for food safety analysis
Devaraj Sabarinathan,
Arumugam Selva Sharma,
Marimuthu Murugavelu,
Balakrishnan Kirubasankar,
Indhiradevi Balusamy,
Zhang Han,
Huanhuan Li,
Quansheng Chen
Affiliations
Devaraj Sabarinathan
School of Food and Biological Engineering, Jiangsu University, Zhenjiang, PR China; Athenese Dx Pvt Ltd, Chennai, Tamilnadu, India; Corresponding author. Department of Food science and Engineering, Jiangsu University, Zhenjiang, China.
Arumugam Selva Sharma
School of Food and Biological Engineering, Jiangsu University, Zhenjiang, PR China
Marimuthu Murugavelu
School of Food and Biological Engineering, Jiangsu University, Zhenjiang, PR China
Balakrishnan Kirubasankar
Department of Energy Science, Sungkyunkwan University, Suwon, South Korea
Indhiradevi Balusamy
Department of Pediatrics, Kanchi Kamakoti Childs Trust Hospital, Chennai, India
Zhang Han
School of Food and Biological Engineering, Jiangsu University, Zhenjiang, PR China
Huanhuan Li
School of Food and Biological Engineering, Jiangsu University, Zhenjiang, PR China; Corresponding author.
Quansheng Chen
School of Food and Biological Engineering, Jiangsu University, Zhenjiang, PR China; Corresponding author.
The development of nanoclusters based on incorporating biomolecules like proteins, lipids, enzymes, DNA, surfactants, and chemical stabilizers creates a stable and high fluorescence bio-sensors promising future due to their high sensitivity, high level of detection and better selectivity. This review addresses a comprehensive and systematic overview of the recent development in synthesizing metal nanocluster by various strategized synthesis techniques. Significantly, the application of nanometal clusters for the detection of various food contaminants such as microorganisms, antibodies, drugs, pesticides, metal contaminants, amino acids, and other food flavors have been discussed briefly concerning the detection techniques, sensitivity, selectivity, and lower limit of detection. The review further gives a brief account on the future prospects in the synthesis of novel metal nanocluster-based biosensors, and their advantages, shortcomings, and potential perspectives toward their application in the field of food safety analysis.
