Tryptase in children in the practice of an allergist

Abstract

The normal serum tryptase level is 0–11.4 ng/ml. Hypertryptasemia occurs with anaphylaxis, systemic mastocytosis, and cutaneous mastocytosis in children. Recently, mast cell activation syndromes are increasingly being diagnosed. The article discusses the main reasons for the increase in the concentration of tryptase in children. Allergists must correctly interpret its causes.

Keywords

• tryptase
• diagnosis
• anaphylaxis
• mastocytosis