Blood clot in Regenerative Endodontic Therapy of Immature Permanent Teeth: a review of the literature

Abstract

Pulp necrosis is diagnosed when the pulp is presented asymptomatic in response to pulp tests. Its conventional management in immature permanent teeth is by apexification. However, this treatment has the disadvantage of weakening the root walls tending to root fracture and pulp does not present revitalization. Due to that, the use of regenerative endodontic treatment has been recommended and it aims to regenerate the dentin-pulp complex, in addition to root growth, maturation and apical closure through cell replacement within the root tissue using stem cells and growth factors. Cloth formation is used as a scaffold for stem cells from the apical papilla to stimulate tissue regeneration. The aim of this review is to synthesize the available information about this treatment and to contribute to the possibility of the creation of a protocol consensus of this treatment.

Keywords

• blood clot
• , regenerative endodontics
• pulp revascularization
• immature permanent teeth
• pulp necrosis