Nopal Cactus (Opuntia ficus-indica) as a Source of Bioactive Compounds for Nutrition, Health and Disease
Karym El-Mostafa,
Youssef El Kharrassi,
Asmaa Badreddine,
Pierre Andreoletti,
Joseph Vamecq,
M'Hammed Saïd El Kebbaj,
Norbert Latruffe,
Gérard Lizard,
Boubker Nasser,
Mustapha Cherkaoui-Malki
Affiliations
Karym El-Mostafa
Laboratoire Bio-PeroxIL, EA7270 University of Bourgogne, 6 Bd Gabriel, Dijon F-21000, France
Youssef El Kharrassi
Laboratoire Bio-PeroxIL, EA7270 University of Bourgogne, 6 Bd Gabriel, Dijon F-21000, France
Asmaa Badreddine
Laboratoire Bio-PeroxIL, EA7270 University of Bourgogne, 6 Bd Gabriel, Dijon F-21000, France
Pierre Andreoletti
Laboratoire Bio-PeroxIL, EA7270 University of Bourgogne, 6 Bd Gabriel, Dijon F-21000, France
Joseph Vamecq
Inserm and HMNO, CBP, CHRU Lille, Lille 59037, France
M'Hammed Saïd El Kebbaj
Laboratoire de recherche sur les Lipoprotéines et l'Athérosclérose, Faculté des Sciences Ben M'sik, Avenue Cdt Driss El Harti BP. 7955, Université Hassan II-Mohammedia-Casablanca, Casablanca 20 000, Morocco
Norbert Latruffe
Laboratoire Bio-PeroxIL, EA7270 University of Bourgogne, 6 Bd Gabriel, Dijon F-21000, France
Gérard Lizard
Inserm and Laboratoire Bio-PeroxIL, EA7270 University of Bourgogne, 6 Bd Gabriel, Dijon F-21000, France
Boubker Nasser
Laboratoire de Biochimie et Neurosciences, Faculté des Sciences et Techniques, Université Hassan I, BP 577, Settat 26 000, Morocco
Mustapha Cherkaoui-Malki
Laboratoire Bio-PeroxIL, EA7270 University of Bourgogne, 6 Bd Gabriel, Dijon F-21000, France
Opuntia ficus-indica, commonly referred to as prickly pear or nopal cactus, is a dicotyledonous angiosperm plant. It belongs to the Cactaceae family and is characterized by its remarkable adaptation to arid and semi-arid climates in tropical and subtropical regions of the globe. In the last decade, compelling evidence for the nutritional and health benefit potential of this cactus has been provided by academic scientists and private companies. Notably, its rich composition in polyphenols, vitamins, polyunsaturated fatty acids and amino acids has been highlighted through the use of a large panel of extraction methods. The identified natural cactus compounds and derivatives were shown to be endowed with biologically relevant activities including anti-inflammatory, antioxidant, hypoglycemic, antimicrobial and neuroprotective properties. The present review is aimed at stressing the major classes of cactus components and their medical interest through emphasis on some of their biological effects, particularly those having the most promising expected health benefit and therapeutic impacts.