FUNCTIONAL CONDITION OF THE MYOCARDIUM IN ACUTE CORONARY SYNDROME

Abstract

The study included 127 patients with various courses of angina and was targeted at the evaluation of myocardial functional condition with the usage of Doppler echo and Holter monitoring. LV systolic and diastolic functions, frequency, duration and prognostic relevance of silent ischemia episodes were assessed. Patients with acute coronary syndrome were divided into groups: 44 patients with I classunstable angina and 41 with I-II class unstable angina. Group of comparison consisted of 42 patients with stable angina II functional class. We have found the severity of myocardial ischemia to be directly related to the severity of angina. A severe course of ACS – unstable angina II-III class – is characterized by a high incidence and duration of silent ischemia episodes, as well as by unfavorable outcome. We have found impaired systolic and diastolic LV function in ACS. We have shown doppler parameters of transmitral flow in I class unstable angina to correlate with the I type of diastolic disfunction; a restrictive type of LV filling has been found in II-III class unstable angina.

Keywords

• acute coronary syndrome
• silent myocardial ischemia
• systolic and diastolic left ventricle disfunction