Simulating nephron ion transport function using activated wafer electrodeionization

Christa N. Hestekin; Jamie A. Hestekin; Sadia Paracha; Grace Morrison; Efecan Pakkaner; John Moore; Leticia Santos de Souza; Sam Stephens; Catey Atchley; Ira Kurtz

doi:10.1038/s43246-020-0016-3

Communications Materials (Apr 2020)

Simulating nephron ion transport function using activated wafer electrodeionization

Christa N. Hestekin,
Jamie A. Hestekin,
Sadia Paracha,
Grace Morrison,
Efecan Pakkaner,
John Moore,
Leticia Santos de Souza,
Sam Stephens,
Catey Atchley,
Ira Kurtz

Affiliations

Christa N. Hestekin: Ralph E. Martin Department of Chemical Engineering, University of Arkansas, 3202 Bell Engineering Center
Jamie A. Hestekin: Ralph E. Martin Department of Chemical Engineering, University of Arkansas, 3202 Bell Engineering Center
Sadia Paracha: Ralph E. Martin Department of Chemical Engineering, University of Arkansas, 3202 Bell Engineering Center
Grace Morrison: Ralph E. Martin Department of Chemical Engineering, University of Arkansas, 3202 Bell Engineering Center
Efecan Pakkaner: Ralph E. Martin Department of Chemical Engineering, University of Arkansas, 3202 Bell Engineering Center
John Moore: Ralph E. Martin Department of Chemical Engineering, University of Arkansas, 3202 Bell Engineering Center
Leticia Santos de Souza: Ralph E. Martin Department of Chemical Engineering, University of Arkansas, 3202 Bell Engineering Center
Sam Stephens: Ralph E. Martin Department of Chemical Engineering, University of Arkansas, 3202 Bell Engineering Center
Catey Atchley: Ralph E. Martin Department of Chemical Engineering, University of Arkansas, 3202 Bell Engineering Center
Ira Kurtz: Department of Medicine, Division of Nephrology, David Geffen School of Medicine, University of California

DOI: https://doi.org/10.1038/s43246-020-0016-3
Journal volume & issue: Vol. 1, no. 1
pp. 1 – 10

Abstract

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The nephrons in the kidney transport ions and organic molecules, but may not work effectively in patients with kidney disease. Here, a synthetic nephron is created, based on activated wafer electrodeionization, and shown to enable the transport of several physiologically relevant ions.

Published in Communications Materials

ISSN: 2662-4443 (Online)
Publisher: Nature Portfolio
Country of publisher: United States
LCC subjects: Technology: Electrical engineering. Electronics. Nuclear engineering: Materials of engineering and construction. Mechanics of materials
Website: https://www.nature.com/commsmat/

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