Nature Communications (Feb 2021)
A glucose meter interface for point-of-care gene circuit-based diagnostics
- Evan Amalfitano,
- Margot Karlikow,
- Masoud Norouzi,
- Katariina Jaenes,
- Seray Cicek,
- Fahim Masum,
- Peivand Sadat Mousavi,
- Yuxiu Guo,
- Laura Tang,
- Andrew Sydor,
- Duo Ma,
- Joel D. Pearson,
- Daniel Trcka,
- Mathieu Pinette,
- Aruna Ambagala,
- Shawn Babiuk,
- Bradley Pickering,
- Jeff Wrana,
- Rod Bremner,
- Tony Mazzulli,
- David Sinton,
- John H. Brumell,
- Alexander A. Green,
- Keith Pardee
Affiliations
- Evan Amalfitano
- Leslie Dan Faculty of Pharmacy, University of Toronto
- Margot Karlikow
- Leslie Dan Faculty of Pharmacy, University of Toronto
- Masoud Norouzi
- Leslie Dan Faculty of Pharmacy, University of Toronto
- Katariina Jaenes
- Leslie Dan Faculty of Pharmacy, University of Toronto
- Seray Cicek
- Leslie Dan Faculty of Pharmacy, University of Toronto
- Fahim Masum
- Leslie Dan Faculty of Pharmacy, University of Toronto
- Peivand Sadat Mousavi
- Leslie Dan Faculty of Pharmacy, University of Toronto
- Yuxiu Guo
- Leslie Dan Faculty of Pharmacy, University of Toronto
- Laura Tang
- Leslie Dan Faculty of Pharmacy, University of Toronto
- Andrew Sydor
- Program in Cell Biology, Hospital for Sick Children, Peter Gilgan Center for Research and Learning
- Duo Ma
- Biodesign Center for Molecular Design and Biomimetics, The Biodesign Institute and the School of Molecular Sciences
- Joel D. Pearson
- Lunenfeld Tanenbaum Research Institute, Mt Sinai Hospital, Sinai Health System
- Daniel Trcka
- Lunenfeld Tanenbaum Research Institute, Mt Sinai Hospital, Sinai Health System
- Mathieu Pinette
- Canadian Food Inspection Agency, National Centre for Foreign Animal Disease
- Aruna Ambagala
- Canadian Food Inspection Agency, National Centre for Foreign Animal Disease
- Shawn Babiuk
- Canadian Food Inspection Agency, National Centre for Foreign Animal Disease
- Bradley Pickering
- Canadian Food Inspection Agency, National Centre for Foreign Animal Disease
- Jeff Wrana
- Lunenfeld Tanenbaum Research Institute, Mt Sinai Hospital, Sinai Health System
- Rod Bremner
- Lunenfeld Tanenbaum Research Institute, Mt Sinai Hospital, Sinai Health System
- Tony Mazzulli
- Department of Laboratory Medicine and Pathobiology, University of Toronto
- David Sinton
- Department of Mechanical and Industrial Engineering, University of Toronto
- John H. Brumell
- Program in Cell Biology, Hospital for Sick Children, Peter Gilgan Center for Research and Learning
- Alexander A. Green
- Biodesign Center for Molecular Design and Biomimetics, The Biodesign Institute and the School of Molecular Sciences
- Keith Pardee
- Leslie Dan Faculty of Pharmacy, University of Toronto
- DOI
- https://doi.org/10.1038/s41467-020-20639-6
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 10
Abstract
Getting synthetic biology circuit-based sensors into field applications is still a challenge. Here the authors combine a circuit sensor with a glucose meter for small analyte and nucleic acid detection.
