Complement inhibition in severe COVID-19 – Blocking C5a seems to be key

• Endry H.T. Lim,
• Alexander P.J. Vlaar,
• Sanne de-Bruin,
• Matthijs C. Brouwer,
• Diederik van-de-Beek

Affiliations

Endry H.T. Lim

Department of Intensive Care Medicine, Amsterdam University Medical Center, University of Amsterdam, Amsterdam UMC, 1100DD Amsterdam, the Netherlands

Alexander P.J. Vlaar

Department of Intensive Care Medicine, Amsterdam University Medical Center, University of Amsterdam, Amsterdam UMC, 1100DD Amsterdam, the Netherlands; Corresponding author.

Sanne de-Bruin

Department of Intensive Care Medicine, Amsterdam University Medical Center, University of Amsterdam, Amsterdam UMC, 1100DD Amsterdam, the Netherlands

Matthijs C. Brouwer

Department of Neurology, Amsterdam Neuroscience, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands

Diederik van-de-Beek

Department of Neurology, Amsterdam Neuroscience, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands