Lymph Node Involvement In Upper Aerodigestive Tract Cancers - A Clinical Study at Specialities University Hospital of Rabat.

International Journal of Medicine and Surgery. 2014;1(2):49-52 DOI 10.15342/ijms.v1i2.56

 

Journal Homepage

Journal Title: International Journal of Medicine and Surgery

ISSN: 2336-0313 (Online)

Publisher: Mediterranean BioMedical Journals

LCC Subject Category: Medicine: Medicine (General) | Medicine: Surgery | Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens

Country of publisher: Morocco

Language of fulltext: French, English

Full-text formats available: PDF, HTML

 

AUTHORS

Rajae BORKI (Department of Otolaryngology, Head and Neck Surgery, Specialties Hospital, Rabat.)
Ali Elayoubi (Department of Otolaryngology, Head and Neck Surgery, Specialties Hospital, Rabat.)
Razika Bencheikh (Department of Otolaryngology, Head and Neck Surgery, Specialties Hospital, Rabat.)
Abdelilah Oujilal (Department of Otolaryngology, Head and Neck Surgery, Specialties Hospital, Rabat.)
Anass Benbouzid (Department of Otolaryngology, Head and Neck Surgery, Specialties Hospital, Rabat.)
Leila Essakalli (Department of Otolaryngology, Head and Neck Surgery, Specialties Hospital, Rabat.)

EDITORIAL INFORMATION

Peer review

Editorial Board

Instructions for authors

Time From Submission to Publication: 8 weeks

 

Abstract | Full Text

<p><strong>Introduction:</strong> Cervical lymph node involvement has a major impact on prognosis and treatment decisions in patients with upper aerodigestive tract (UADT) cancer.</p><p><strong>Objective:</strong> The aim of this study was to assess the incidence and pattern of cervical lymph node (LN) metastases in cancers of the upper aerodigestive tract</p><p><strong>Methods:</strong> This prospective study was conducted by the Department of ENT and Maxillofacial Surgery at Specialities University Hospital of Rabat, collecting data between October 2009 and December 2011. Lymph nodes were counted, clinically and radiologically localized, excised, then studied histologically.</p><p><strong>Results:</strong> During this period, 106 patients have been treated surgically with a recent diagnosis of UADT cancer. The average age of our patients was 55±13.3 years, while male/female ratio was 3.5 to 1. More than half of our patients were operated with cancer of the larynx (58.5%, n=62); 27.4% (n=29) of patients suffered from oral cavity cancer and 14.2% (n=15) had cancer of the hypopharinx. Cervical lymph node invasion was estimated at 31.2% clinically, and 38.7% radiologically and histologically, distributed in different sites.</p><p>Although the percentage of the invasion is almost similar clinically, radiologically and histologically, the high number of false positives and true negatives according to clinical and radiological exams confirms that specificity and sensitivity of these two exams is still poor compared to histology.</p><p><strong>Conclusion:</strong> Thus, cervical metastases have to be diagnosed histologically. Moreover, the low percentage of lymph node invasions in the case of a UADT cancer suggests that the use of sentinel lymph node technique could be important, as it has been validated for small T1T2N0 tumors in the oral cavity. Further studies are needed to confirm its validity in case of other UADT tumor types.</p>