Pharyngeal-Cervical-Brachial (PCB) variant of Guillain Barre Syndrome

Abstract

The Pharyngeal- Cervical-Brachial (PCB) variant of Guillain- Barre Syndrome (GBS) is a rare presentation, characterized by marked weakness of the oro- pharynx, neck and proximal upper limbs sparing power and reflexes of the lower limbs. It presents as rapid progressive pharyngeal weakness and often needs intubation and ventilation due to excessive secretions. Diagnosis is supported by high CSF protein and absent F waves in upper limbs in electro-physiological studies. Diagnosis can be confirmed by doing ant DT1a antibodies. We present the case report of a 6-year-old patient who presented with progressive difficulty in swallowing due to oro-pharyngeal muscle weakness.

Keywords

• guillain- barre syndrome
• pharyngeal- cervical-brachial variant