Emerging Infectious Diseases (Nov 2021)

Mutations Associated with SARS-CoV-2 Variants of Concern, Benin, Early 2021

  • Anna-Lena Sander,
  • Anges Yadouleton,
  • Edmilson F. de Oliveira Filho,
  • Carine Tchibozo,
  • Gildas Hounkanrin,
  • Yvette Badou,
  • Praise Adewumi,
  • Keke K. René,
  • Dossou Ange,
  • Salifou Sourakatou,
  • Eclou Sedjro,
  • Melchior A. J. Aïssi,
  • Hinson Fidelia,
  • Mamoudou Harouna Djingarey,
  • Michael Nagel,
  • Wendy Karen Jo,
  • Andres Moreira-Soto,
  • Christian Drosten,
  • Olfert Landt,
  • Victor Max Corman,
  • Benjamin Hounkpatin,
  • Jan Felix Drexler

DOI
https://doi.org/10.3201/eid2711.211353
Journal volume & issue
Vol. 27, no. 11
pp. 2889 – 2903

Abstract

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Intense transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Africa might promote emergence of variants. We describe 10 SARS-CoV-2 lineages in Benin during early 2021 that harbored mutations associated with variants of concern. Benin-derived SARS-CoV-2 strains were more efficiently neutralized by antibodies derived from vaccinees than patients, warranting accelerated vaccination in Africa.

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