DIABETES MELLITUS AND THE PROCESS OF CUTANEOUS HEALING

Abstract

The objective of this updating study was to address the molecular and cellular process of the healing of cutaneous wounds in individuals with diabetes mellitus. The process of tissue repair in individuals with diabetes mellitus is slowed down; the excessive production of Reactive oxygen species, the reduction of Nitric Oxide, the reduction in the response to Growth Factors and the reduction in the proteins of the insulin signalling route are all involved in this process. Success in treating wounds which are having difficulty in healing depends on knowledge of the factors which interfere in this process, which, allied with clinical practice, provides the nurse with support for prevention, interventions and choice of appropriate dressings for the care and treatment of wounds in patients with diabetes mellitus.

Keywords

• Healing
• Diabetes mellitus
• Nursing