مجله دانشکده پزشکی اصفهان (Dec 2014)
Evaluation of the Success Rate of Assisted Reproductive Techniques (ART) in Shahid Beheshti Infertility Center, Isfahan, Iran
Abstract
Background: Today, usage of assisted reproductive techniques (ART) has been resolved the problem of many infertile couples. Repeated treatment cycles, long time and high cost, problems due to repeated anesthesia, has been directed the researchers to find ways to predict the success rate of each method. This study aimed to evaluate the success of assisted reproductive techniques in Isfahan Shahid Beheshti infertility center, Iran. Methods: In this retrospective study, 71 couples referred to this center for assisted reproductive techniques during the first six months of 2013 were enrolled. The main criterion for a positive result was clinical pregnancy two weeks after embryo transfer. Required information such as age, semen analysis and outcome of assisted reproductive techniques, were obtained from patients' medical records. Findings: Of all couples, 42 cases were treated with intrauterine insemination (IUI) and 29 cases were treated with in-vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI). 23.8% of IUI cycles and 24.1% of IVF/ICSI cycles were successful. The mean age and duration of infertility in both successful and unsuccessful IUI groups were not statistically significant; while these diferences in the cases of IVF/ICSI were significant. In addition, there were no significant differences between the sperm parameters in successful and unsuccessful IUI treated groups; but in IVF/ICSI treated group, we found significant differences in the percent of fast motile sperms between successful and unsuccessful groups. Conclusion: Conventional analysis of semen and couple’s age cannot predict the outcome of IUI; but the success rate of IVF/ICSI is related to the age of couples, as well as shorter duration of infertility and better semen parameters.
