Giant congenital melanocytic nevus with neurofibroma-like lesions and onset of vitiligo

Abstract

Giant congenital pigmented nevus and neurofibromatosis type 1 may rarely occur together. We reported here an unusual case where giant congenital melanocytic nevus was associated with neurofibroma-like lesions and vitiligo, emphasizing the clinical and histological diagnostic difficulties posed by this presentation, the signification of vitiligo which can testify of a possible malignant transformation of the giant nevus to a melanoma, and highlights the importance of an accurate diagnosis and a close follow-up of such patients.

Keywords

• Giant congenital melanocytic nevus
• Neurofibromatosis
• Melanoma
• Vitiligo
• Neurotization