Research Progress on the Correlation between the Intestinal Microbiota and Food Allergy
Hui Yang,
Yezhi Qu,
Yaran Gao,
Shuyuan Sun,
Rina Wu,
Junrui Wu
Affiliations
Hui Yang
Key Laboratory of Microbial Fermentation Technology Innovation, Engineering Research Center of Food Fermentation Technology, College of Food Science, Shenyang Agricultural University, Shenyang 110866, China
Yezhi Qu
Key Laboratory of Microbial Fermentation Technology Innovation, Engineering Research Center of Food Fermentation Technology, College of Food Science, Shenyang Agricultural University, Shenyang 110866, China
Yaran Gao
Key Laboratory of Microbial Fermentation Technology Innovation, Engineering Research Center of Food Fermentation Technology, College of Food Science, Shenyang Agricultural University, Shenyang 110866, China
Shuyuan Sun
Key Laboratory of Microbial Fermentation Technology Innovation, Engineering Research Center of Food Fermentation Technology, College of Food Science, Shenyang Agricultural University, Shenyang 110866, China
Rina Wu
Key Laboratory of Microbial Fermentation Technology Innovation, Engineering Research Center of Food Fermentation Technology, College of Food Science, Shenyang Agricultural University, Shenyang 110866, China
Junrui Wu
Key Laboratory of Microbial Fermentation Technology Innovation, Engineering Research Center of Food Fermentation Technology, College of Food Science, Shenyang Agricultural University, Shenyang 110866, China
The increasing incidence of food allergy is becoming a substantial public health concern. Increasing evidence suggests that alterations in the composition of the intestinal microbiota play a part in the development of food allergy. Additionally, the application of probiotics to correct gut microbiota imbalances and regulate food allergy has become a research hotspot. However, the mechanism by which the gut microbiota regulates food allergy and the efficacy of probiotics are still in the preliminary exploration stage, and there are no clear and specific conclusions. The aim of this review is to provide information regarding the immune mechanism underlying food allergy, the correlation between the intestinal microbiota and food allergy, a detailed description of causation, and mechanisms by which the intestinal microbiota regulates food allergy. Subsequently, we highlight how probiotics modulate the gut microbiome–immune axis to alleviate food allergy. This study will contribute to the dovetailing of bacterial therapeutics with immune system in allergic individuals to prevent food allergy and ameliorate food allergy symptoms.