Nature Communications (Mar 2019)

The development of synaptic transmission is time-locked to early social behaviors in rats

  • Shovan Naskar,
  • Roberto Narducci,
  • Edoardo Balzani,
  • Andrzej W. Cwetsch,
  • Valter Tucci,
  • Laura Cancedda

DOI
https://doi.org/10.1038/s41467-019-09156-3
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 12

Abstract

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The development of functional synapses is a key milestone in neurodevelopment. Here, the authors show how serotonin signalling coordinates development of glutamatergic and GABAergic currents and triggers the emergence of integrative behavior (huddling) in rat pups.