Egyptian Pediatric Association Gazette (Apr 2022)
Learned lesson from COVID-19: can routine immunizations be the first line of defense against the next pandemic?
- Antoine AbdelMassih,
- Hanya Gaber,
- Meryam El Shershaby,
- Maram Hanafy,
- Yasmin Omar,
- Reem Husseiny,
- Nada AlShehry,
- Habiba-Allah Ismail,
- Aya Kamel,
- Rafeef Hozaien,
- Ghadeer Khaled,
- Mohamed Amer,
- Aya Turki,
- Heba Fawzy,
- Stefano Puligheddu,
- Dalia Khaled,
- Nardine Nasry Thabet,
- Mariam Sherif Abdelaziz,
- Mustafa Barakat,
- Sara Sharaf,
- Ahmed Mohamed,
- Dina Mohsen,
- Amr El Feky,
- Hadil Adly,
- Eman Ibrahim,
- Rana Mahmoud,
- Mirna Reda,
- Felopateer Riad,
- Carmen Vasile,
- Mahitab Adel Shohdi,
- Nadine Hesham,
- Nadine El-Husseiny,
- Rana Ragy,
- Raghda Fouda
Affiliations
- Antoine AbdelMassih
- Pediatric Department, Pediatric Cardiology Unit, Faculty of Medicine, Cairo University
- Hanya Gaber
- Student and Internship research program (Research Accessibility Team), Faculty of Medicine, Cairo University
- Meryam El Shershaby
- Student and Internship research program (Research Accessibility Team), Faculty of Medicine, Cairo University
- Maram Hanafy
- Student and Internship research program (Research Accessibility Team), Faculty of Medicine, Cairo University
- Yasmin Omar
- Student and Internship research program (Research Accessibility Team), Faculty of Medicine, Cairo University
- Reem Husseiny
- Student and Internship research program (Research Accessibility Team), Faculty of Medicine, Cairo University
- Nada AlShehry
- Student and Internship research program (Research Accessibility Team), Faculty of Medicine, Cairo University
- Habiba-Allah Ismail
- Student and Internship research program (Research Accessibility Team), Faculty of Medicine, Cairo University
- Aya Kamel
- Student and Internship research program (Research Accessibility Team), Faculty of Medicine, Cairo University
- Rafeef Hozaien
- Student and Internship research program (Research Accessibility Team), Faculty of Medicine, Cairo University
- Ghadeer Khaled
- Student and Internship research program (Research Accessibility Team), Faculty of Medicine, Cairo University
- Mohamed Amer
- Student and Internship research program (Research Accessibility Team), Faculty of Medicine, Cairo University
- Aya Turki
- Student and Internship research program (Research Accessibility Team), Faculty of Medicine, Cairo University
- Heba Fawzy
- Student and Internship research program (Research Accessibility Team), Faculty of Medicine, Cairo University
- Stefano Puligheddu
- Student and Internship research program (Research Accessibility Team), Faculty of Medicine, Cairo University
- Dalia Khaled
- Student and Internship research program (Research Accessibility Team), Faculty of Medicine, Cairo University
- Nardine Nasry Thabet
- Student and Internship research program (Research Accessibility Team), Faculty of Medicine, Cairo University
- Mariam Sherif Abdelaziz
- Student and Internship research program (Research Accessibility Team), Faculty of Medicine, Cairo University
- Mustafa Barakat
- Student and Internship research program (Research Accessibility Team), Faculty of Medicine, Cairo University
- Sara Sharaf
- Student and Internship research program (Research Accessibility Team), Faculty of Medicine, Cairo University
- Ahmed Mohamed
- Student and Internship research program (Research Accessibility Team), Faculty of Medicine, Cairo University
- Dina Mohsen
- Student and Internship research program (Research Accessibility Team), Faculty of Medicine, Cairo University
- Amr El Feky
- Student and Internship research program (Research Accessibility Team), Faculty of Medicine, Cairo University
- Hadil Adly
- Student and Internship research program (Research Accessibility Team), Faculty of Medicine, Cairo University
- Eman Ibrahim
- Student and Internship research program (Research Accessibility Team), Faculty of Medicine, Cairo University
- Rana Mahmoud
- Student and Internship research program (Research Accessibility Team), Faculty of Medicine, Cairo University
- Mirna Reda
- Student and Internship research program (Research Accessibility Team), Faculty of Medicine, Cairo University
- Felopateer Riad
- Student and Internship research program (Research Accessibility Team), Faculty of Medicine, Cairo University
- Carmen Vasile
- Student and Internship research program (Research Accessibility Team), Faculty of Medicine, Cairo University
- Mahitab Adel Shohdi
- Student and Internship research program (Research Accessibility Team), Faculty of Medicine, Cairo University
- Nadine Hesham
- Student and Internship research program (Research Accessibility Team), Faculty of Medicine, Cairo University
- Nadine El-Husseiny
- Faculty of Dentistry, Cairo University
- Rana Ragy
- Student and Internship research program (Research Accessibility Team), Faculty of Medicine, Cairo University
- Raghda Fouda
- Clinical and Chemical Pathology Department, Faculty of Medicine, Cairo University
- DOI
- https://doi.org/10.1186/s43054-022-00105-2
- Journal volume & issue
-
Vol. 70,
no. 1
pp. 1 – 9
Abstract
Abstract Background Single-cell sequencing studies on the lung microenvironment have revealed that the outcome of COVID-19 depends largely on the immune system response rather than the viral load. A robust innate immune response and a regulated adaptive immunity can prevent the worst outcomes such as hospitalization and the need for mechanical ventilation. Main body Intriguingly, several vaccines pertaining to the routine vaccination schedule, not only BCG, can skew the immune response towards the aforementioned beneficial effects. Short conclusion This means that routine immunization not only can help in the current pandemic but can also offer a rapid rescue in the subsequent epidemics or pandemics until a vaccine is developed.
Keywords
