Pifu-xingbing zhenliaoxue zazhi (Jun 2023)

Telangiectasia macularis eruptiva perstans: a report of two cases

  • Qiufeng HUANG,
  • Yong SHAO,
  • Jie ZHANG,
  • Bo YU,
  • Xiaoping HU

DOI
https://doi.org/10.3969/j.issn.1674-8468.2023.03.013
Journal volume & issue
Vol. 30, no. 3
pp. 257 – 261

Abstract

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Patient one was a 38-year-old man with a 20-year history of red macules and angiotelectasis on the chest and the upper arms. Dermatological examination showed multiple telangiectatic macules on the chest and the upper arms, with a negative Darier's sign. Histopathology revealed mild epidermal atrophy, hyaline degeneration and scattered vasodilation in the superficial dermis. Perivascular infiltration of lymphocytes and mast cells was evident in the superficial dermis. CD117 staining demonstrated perivascular infiltration of mast cells in the dermis. Diagnosis: telangiectasia macularis eruptiva perstans. Patient two was a 49-year-old man with red macules and angiotelectasis on the trunk and the arms for over 2 years. Dermatological examination revealed demarcated erythematous maculopapular rashes on the upper limbs, the chest and the back, with a negative Darier's sign. Histopathological findings included reticular keratosis, perivascular infiltration of mast cells in the superficial dermis, and proliferation of collagen fibers. Toluidine blue staining showed degranulation of perivascular mast cells. The diagnosis was telangiectasia macularis eruptiva perstans. Both patient were treated with oral ketotifen at a dose of 1 mg/evening. They claimed no significant improvement after one-month treatments.

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