395 Detection of viral antigen and immune activation after intra-tumor injection of CAN-3110 (ICP-34.5 expressing HSV-1 oncolytic virus) in patients with recurrent high-grade glioma

• Francesca Barone,
• Hiroshi Nakashima,
• James Grant,
• David Reardon,
• Kai Wucherpfennig,
• Patrick Wen,
• Sean Lawler,
• Estuardo Aguilar-Cordova,
• Laura Aguilar,
• Brian Guzik,
• E Antonio Chiocca,
• Scott Rodig,
• Jessica Dwyer,
• Isaac Soloman,
• Daniel Triggs,
• Abigail Tianai Zhang,
• Yu Zeng,
• Jared Woods,
• Eudocia Quant Lee,
• Keith Ligon,
• William Pisano,
• Mario Suva,
• Sascha Marx,
• Simon Gritsch,
• Nathan Mathewson,
• David Krisky,
• Paul Tak

Affiliations

Francesca Barone

6 RRG, Institute of Inflamation and Ageing, University of Birmingham, Birmingham, UK, UK

Hiroshi Nakashima

13Department of Preventive Medicine and Public Health, National Defense Medical College, Tokorozawa, Saitama, Japan

James Grant

Quality Improvement Academy, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK

David Reardon

2Dana Farber Cancer Institute, Boston, MA, USA

Kai Wucherpfennig

3Dana-Farber Cancer Institute, Boston, MA, USA

Patrick Wen

9Dana Farber Cancer Institute, Boston, MA, USA

Sean Lawler

1Brigham and Women’s Hospital, Boston, MA, USA

Estuardo Aguilar-Cordova

2Advantagene Inc, Needham, MA, USA

Laura Aguilar

2Advantagene Inc, Needham, MA, USA

Brian Guzik

2Advantagene Inc, Needham, MA, USA

E Antonio Chiocca

1Brigham and Women’s Hospital, Boston, MA, USA

Scott Rodig

7Brigham and Women’s Hospital and Harvard, Boston, MA, USA

Jessica Dwyer

1Candel Therapeutics, Inc., Needham, MA, USA

Isaac Soloman

3Brigham and Women’s Hospital, Boston, MA, USA

Daniel Triggs

3Brigham and Women’s Hospital, Boston, MA, USA

Abigail Tianai Zhang

2Brigham and Women’s Hosptial, Boston, MA, USA

Yu Zeng

4Dana-Farber Cancer Institute, Boston, MA, USA

Jared Woods

4Dana-Farber Cancer Institute, Boston, MA, USA

Eudocia Quant Lee

3Brigham and Women’s Hospital, Boston, MA, USA

Keith Ligon

4Dana-Farber Cancer Institute, Boston, MA, USA

William Pisano

4Dana-Farber Cancer Institute, Boston, MA, USA

Mario Suva

5Massachusetts General Hosptial, Boston, MA, USA

Sascha Marx

4Dana-Farber Cancer Institute, Boston, MA, USA

Simon Gritsch

6Massachusetts General Hospital, Boston, MA, USA

Nathan Mathewson

4Dana-Farber Cancer Institute, Boston, MA, USA

David Krisky

1Candel Therapeutics, Inc., Needham, MA, USA

Paul Tak

1Candel Therapeutics, Inc., Needham, MA, USA