Refined Quantification of Infection Bottlenecks and Pathogen Dissemination with STAMPR

Karthik Hullahalli; Justin R. Pritchard; Matthew K. Waldor

doi:10.1128/mSystems.00887-21

mSystems (Aug 2021)

Refined Quantification of Infection Bottlenecks and Pathogen Dissemination with STAMPR

Karthik Hullahalli,
Justin R. Pritchard,
Matthew K. Waldor

Affiliations

Karthik Hullahalli: ORCiD; Department of Microbiology, Harvard Medical School, Boston, Massachusetts, USA
Justin R. Pritchard: Department of Biomedical Engineering, Penn State University, University Park, Pennsylvania, USA
Matthew K. Waldor: ORCiD; Department of Microbiology, Harvard Medical School, Boston, Massachusetts, USA

DOI: https://doi.org/10.1128/mSystems.00887-21
Journal volume & issue: Vol. 6, no. 4

Abstract

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Barcoded bacteria are often employed to monitor pathogen population dynamics during infection. The accuracy of these measurements is diminished by unequal bacterial expansion rates.

Published in mSystems

ISSN: 2379-5077 (Online)
Publisher: American Society for Microbiology
Country of publisher: United States
LCC subjects: Science: Microbiology
Website: https://journals.asm.org/journal/msystems

About the journal